Science Behind Moisturizers: Mechanisms, Uses, and Benefits

Science Behind Moisturizers: Mechanisms, Uses, and Benefits

Maintaining your skin healthy is important for your general health as well as appearance.  Moisturizers are one of the most popular preparations in cosmetics and have been utilized extensively to make skin softer and more resilient. Contemporarily, dry skin wrinkles, pain, tightness, itching, and stinging, can be efficiently treated with moisturizers. It also preserves water balance, which clarifies the importance of water in the stratum corneum (stratum corneum is the outermost layer of the epidermis) that keeps dangerous substances out of the body and stops water loss, as well as maintaining healthy skin physiology and turnover processes (1, 2).

History of Moisturizer

Cosmetics have undoubtedly been around for far earlier, the earliest evidence of them comes from Ancient Egypt, around 6000 years ago. Egyptians frequently use frankincense, myrrh, and aloe. The ancient Egyptians employed these materials as anti-wrinkle lotions because they thought they had anti-aging qualities, especially frankincense (1).

Mechanisms of Action: How Moisturizers Work

Moisturizers function by nourishing the skin and re-establishing its natural barrier function. The humectants, occlusive agents, and emollients found in moisturizers combine to increase skin hydration and stop water loss. Glycerin and hyaluronic acid are examples of humectants that draw water to the skin and contribute to its increased water content. Mineral oil and petrolatum are examples of occlusive substances that create a physical barrier over the skin to prevent water evaporation. By filling the spaces between skin cells, emollients like ceramides and shea butter help to soften and smooth the skin (2, 3).

Types of Moisturizers

2. Occlusive moisturizers: Occlusive moisturizers establish a barrier that prevents water loss or lowers transepidermal water loss (TEWL) from the skin. Because of this barrier, the deeper layers of the epidermis and dermis can refill the level of water in the stratum corneum. The most successful occlusive moisturizer is petroleum oil, which reduces water loss through the epidermis by over 99%. Many other substances can serve as occlusive moisturizers:

Hydrocarbons: Petrolatum, mineral oil, paraffin, squalene

Silicones: Dimethicone

Vegetable oils: Coconut oil, castor oil, olive oil, grape seed oil, soybean oil

Animal Fats: Mink oil, emu oil, lanolin

Wax Esters: Lanolin, beeswax

Sterols: Cholesterol, ceramides

2. Humectants: Humectants are substances that draw in and hold onto water. Among these, urea is an endogenous molecule that makes up the natural moisturizing factor (NMF). More often, humectants pull water from the deeper layers of the epidermis and dermis, but they can hydrate the skin if the humidity is higher than 70%.

    Urea is one of the key components of NMF. Urea is added to moisturizers to aid in water absorption into the stratum corneum. It encourages corneocyte desquamation and improves the absorption of other topically administered drugs.

    Glycerin is another commonly used humectant and it is frequently present in many skincare products. It has positive effects on barrier repair in addition to absorbing and binding water. Honey, sorbitol, propylene glycol, and hyaluronic acid are further humectants.

3. Emulsifiers: Emulsifiers are crucial ingredients in many skincare products, enabling the stable combination of oil and water-based components. While they enhance product texture and facilitate ingredient absorption, but some emulsifiers can potentially disrupt the skin’s natural barrier, leading to dryness, irritation, and even conditions like contact dermatitis. Hence, it selection is equally important as other active ingredients of the moisturizer. Commonly used emulsifiers are fatty acids, like stearic acid.

Choose Moisturizer Based on Your Skin Type

Dry Skin

A moisturizer containing rich, nourishing ingredients like lycerine, ceramides, and shea butter is essential for people with dry skin. Since lightweight or gel-based moisturizers might not sufficiently hydrate skin that is very dry, consumers should stay away from using them. A thicker-textured moisturizer, like ointment or lotion, aids in preserving moisture (1, 2, 3).

Oily Skin

A lightweight, oil-free moisturizer is the best option for people with oily skin because thick, greasy lotions can block pores and lead to illnesses. Individuals should look out for a moisturizer that contains moisturizing yet non-greasy components like lycerine or hyaluronic acid. In my opinion, gel-based moisturizers are typically lighter and easier to absorb, they ought to think about using one (2, 3).

Sensitive Skin

Sensitive skin types should check out moisturizers that are hypoallergenic and fragrance-free because they are less likely to cause irritation. They should stay away from moisturizers with harsh chemicals or preservatives and instead pick one with calming elements like chamomile or aloe vera (2, 3).

Mature Skin

Our skin tends to get thinner and drier as we mature. Hence, in older age, skin texture can be enhanced and wrinkles and fine lines can be lessened using moisturizers that include retinol or peptides. For deeper hydration, older adults should use a moisturizer with a heavier consistency, like an ointment or cream (2, 3).

Best Practices for Moisturizer Use

Application Timing

Apply moisturizer when the skin is slightly damp or moist (e.g., after bathing) to maximize hydration and seal in moisture.

Product Selection

Choose moisturizers with ceramides, humectants (like urea, and lycerine), and emollients for optimal barrier support. Acidic formulations are particularly beneficial for maintaining the skin’s natural pH and supporting the microbiome.

Gentle Cleansing

Use lukewarm water and mild, fragrance-free soaps to avoid stripping the skin of natural oils and exacerbating dryness or irritation.

Summary

More than just beauty goods, moisturizers are vital resources for preserving the integrity of the skin’s barrier, treating dermatological disorders, and promoting skin health. As per the extensive research, I have concluded that every person should choose formulas that are supported by research for optimal effects, and use them frequently on wet skin, especially after washing it gently with lukewarm water and light soaps for better results.

References

(1)   A review of moisturizers; history, preparation, characterization, and applications. Cosmetics. 2022.

(2)   Moisturizers, Starpearls Book. 2024.

(3)   The role of moisturizers in addressing various kinds of dermatitis: a review. Clinical medicine & research. 2017.

Post a Comment

Previous Post Next Post